Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.70 |
| ▸ | LTB4R2 | Q9NPC1 | 19/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417 | 1.00 | AGTR1 (0.70) | AGTR1LTB4R2 | |
| SCHEMBL2097 | 0.91 | LTB4R2 (0.65) | AGTR1LTB4R2 | |
| SCHEMBL2872 | 0.91 | LTB4R2 (0.65) | AGTR1LTB4R2 | |
| SCHEMBL8475874 | 0.89 | LTB4R2 (0.71) | AGTR1LTB4R2 | |
| SCHEMBL8475880 | 0.84 | LTB4R2 (0.69) | AGTR1LTB4R2 | |
| SCHEMBL7298612 | 0.83 | LTB4R2 (0.58) | AGTR1LTB4R2 | |
| SCHEMBL2178 | 0.82 | AGTR1 (0.74) | AGTR1LTB4R2 | |
| SCHEMBL2820 | 0.82 | AGTR1 (0.74) | AGTR1LTB4R2 | |
| SCHEMBL2395 | 0.82 | LTB4R2 (0.75) | AGTR1LTB4R2 | |
| SCHEMBL2394 | 0.82 | LTB4R2 (0.75) | AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |