Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319699 | 0.90 | RAB9A (0.75) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL25318784 | 0.89 | RAB9A (0.56) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28722332 | 0.87 | SMN1; SMN2 (0.79) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28721668 | 0.83 | RAB9A (1.00) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28720259 | 0.83 | RAB9A (0.74) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28721670 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28722577 | 0.82 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28720172 | 0.82 | RAB9A (0.76) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28938138 | 0.81 | RAB9A (0.79) | RAB9ASMN1; SMN2KMT2ATP53NPC1 | |
| SCHEMBL28721484 | 0.81 | RAB9A (0.78) | RAB9ASMN1; SMN2KMT2ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349758-B | Compound with mother nucleus of pyridoimidazole as well as preparation method and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114349758-A | Compound with pyridine imidazole as parent nucleus and preparation method and application thereof | 中国药科大学 | 2022-04-15 | — | — | CN | disclosed |