Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.74 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | PKM | P14618 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693079 | 0.90 | RAB9A (0.60) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL28721484 | 0.88 | RAB9A (0.78) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL28721668 | 0.85 | RAB9A (1.00) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL28722577 | 0.84 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL15652863 | 0.84 | RAB9A (0.71) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL25319699 | 0.84 | RAB9A (0.75) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL28720175 | 0.83 | RAB9A (0.70) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL15693606 | 0.82 | OPRL1 (0.58) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL28722332 | 0.81 | SMN1; SMN2 (0.79) | RAB9ASMN1; SMN2TP53KMT2ANPC1 | |
| SCHEMBL15652518 | 0.81 | OPRL1 (0.60) | RAB9ASMN1; SMN2TP53KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349758-B | Compound with mother nucleus of pyridoimidazole as well as preparation method and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114349758-A | Compound with pyridine imidazole as parent nucleus and preparation method and application thereof | 中国药科大学 | 2022-04-15 | — | — | CN | disclosed |