Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719052 | 0.90 | ACKR3 (0.35) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL28720244 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28720246 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28720242 | 0.76 | GAA (0.43) | SMN1; SMN2PREPKMT2AMEN1ALDH1A1 | |
| SCHEMBL18763395 | 0.76 | GAA (0.43) | SMN1; SMN2PREPKMT2AMEN1ALDH1A1 | |
| SCHEMBL18740602 | 0.73 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL18763261 | 0.71 | KMT2A (0.40) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL18740588 | 0.70 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18740499 | 0.70 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18740587 | 0.70 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368101-B | Selective NR2B antagonists | 百时美施贵宝公司 | 2022-03-15 | — | — | CN | disclosed |