Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL28720372

c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.49
HIF1A Q16665 1/20 0.40
CYP1A2 P05177 2/20 0.34
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
SLC6A2 P23975 2/20 0.31
TAAR1 Q96RJ0 2/20 0.31
MAOA P21397 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2A6 P11509 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
LAP3 P28838 3/20 0.31
CPA1 P15085 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156524 0.94 SNCA (0.53) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Biphenyl SCHEMBL4383101 0.83 SNCA (0.44) SNCAHIF1ACYP1A2ALDH1A1CYP3A4
SCHEMBL29918368 0.82 SNCA (0.65) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Tetraphenylphosphonium SCHEMBL15070 0.82 HIF1A (0.38) HIF1AALDH1A1
Bromide SCHEMBL163158 0.80 SNCA (0.67) SNCAHIF1ACYP1A2EPHX1ALDH1A1
SCHEMBL989761 0.80 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Fluoride Ion SCHEMBL585089 0.80 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Iodide SCHEMBL159922 0.80 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Water SCHEMBL3422802 0.80 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1ALDH1A1
Hydrochloric Acid SCHEMBL494 0.80 SNCA (0.63) SNCAHIF1ACYP1A2EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790357-B Curable modified petroleum resin, preparation method and application thereof 可隆工业株式会社 2022-04-12 CN disclosed