Biphenyl

Biphenyl

SCHEMBL4383101

c1ccc(-c2ccccc2)cc1.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.c1ccc([PH+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.44
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP1A2 P05177 1/20 0.31
ACP3 P15309 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156524 0.88 SNCA (0.53) SNCAHIF1AALDH1A1CYP3A4CYP1A2
Tetraphenylphosphonium SCHEMBL28720372 0.83 SNCA (0.49) SNCAHIF1AALDH1A1CYP3A4CYP1A2
Biphenyl SCHEMBL4385685 0.80 ALDH1A1 (0.45) ALDH1A1CYP3A4CYP1A2TAAR1
SCHEMBL29918368 0.76 SNCA (0.65) SNCAHIF1AALDH1A1CYP1A2TAAR1
SCHEMBL335967 0.76 ALDH1A1 (0.35) ALDH1A1
Bromide SCHEMBL7728204 0.75 SNCA (0.63) SNCAHIF1AALDH1A1CYP3A4ACP3
Hydrochloric Acid SCHEMBL8146357 0.75 SNCA (0.60) SNCAHIF1AALDH1A1CYP3A4ACP3
Bromide SCHEMBL163158 0.74 SNCA (0.67) SNCAHIF1AALDH1A1CYP1A2TAAR1
Fluoride Ion SCHEMBL585089 0.74 SNCA (0.63) SNCAHIF1AALDH1A1CYP1A2TAAR1
SCHEMBL989761 0.74 SNCA (0.63) SNCAHIF1AALDH1A1CYP1A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629431-B2 Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate IDEMITSU KOSAN CO., LTD. (JP) 2009-12-08 US disclosed
US-20080064847-A1 Oxidative carbonylation; molecular weight control IDEMISU KOSAN CO., LTD. (JP) 2008-03-13 US disclosed