Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 9/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23920291 | 0.86 | ATF4 (0.57) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL30578702 | 0.86 | ATF4 (0.57) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL29447037 | 0.85 | ATF4 (0.56) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL22777693 | 0.85 | ATF4 (0.56) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL29082669 | 0.84 | RAB9A (0.62) | HRH3NPC1RAB9AHRH4DPP4 | |
| SCHEMBL28600362 | 0.84 | ATF4 (0.55) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL28722601 | 0.83 | RAB9A (0.50) | ATF4HRH3NPC1RAB9ATAS1R3 | |
| SCHEMBL28722600 | 0.83 | RAB9A (0.50) | ATF4HRH3NPC1RAB9ATAS1R3 | |
| SCHEMBL22777315 | 0.83 | ATF4 (0.56) | ATF4HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL21882069 | 0.82 | ATF4 (0.57) | ATF4HRH3L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206829-A | Integrated stress response pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2022-03-18 | — | — | CN | disclosed |