Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.48 |
| ▸ | ACACA | Q13085 | 5/20 | 0.48 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.47 |
| ▸ | ATF4 | P18848 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23920230 | 1.00 | ACACB (0.48) | ACACBACACAPBKATF4RAB9A | |
| SCHEMBL29527421 | 1.00 | ACACB (0.48) | ACACBACACAPBKATF4RAB9A | |
| SCHEMBL29527441 | 1.00 | ACACB (0.48) | ACACBACACAPBKATF4RAB9A | |
| SCHEMBL21050155 | 0.90 | RAB9A (0.51) | ATF4RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL21050159 | 0.90 | RAB9A (0.51) | ATF4RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL29356799 | 0.90 | RAB9A (0.51) | ATF4RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL22373836 | 0.87 | ACACB (0.43) | ACACBACACAATF4HDAC3HDAC1 | |
| SCHEMBL22777444 | 0.87 | RAB9A (0.54) | ATF4RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL22777445 | 0.87 | RAB9A (0.54) | ATF4RAB9ANPC1HDAC3HDAC1 | |
| SCHEMBL29447009 | 0.87 | RAB9A (0.54) | ATF4RAB9ANPC1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206829-A | Integrated stress response pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2022-03-18 | — | — | CN | disclosed |