SCHEMBL28720484

SCHEMBL28720484

CCCCCCc1cc(Br)sc1Br.[2H]

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.41
TYR P14679 2/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GPR35 Q9HC97 5/20 0.38
LIPG Q9Y5X9 1/20 0.38
PTGS2 P35354 6/20 0.37
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196435 1.00 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL1224883 1.00 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL4388195 1.00 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL197683 1.00 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL16139825 1.00 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL27852766 0.98 ALOX5 (0.40) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL3466429 0.92 TYR (0.37) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL30861670 0.90 MAPT (0.36) MAPT
SCHEMBL30861671 0.90 MAPT (0.36) MAPT
SCHEMBL20526257 0.89 CYP1A2 (0.41) ALOX5TYRCYP3A4MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369081-A Fully deuterated thiophene compound, preparation method thereof, organic intermediate and organic electroluminescent device 安徽秀朗新材料科技有限公司 2022-04-19 CN disclosed