SCHEMBL3466429

SCHEMBL3466429

CCCCc1cc(Br)sc1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.37
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK10 P53779 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SKP2 Q13309 1/20 0.32
TLR8 Q9NR97 1/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197683 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL4388195 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL28720484 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL16139825 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL196435 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL1224883 0.92 ALOX5 (0.41) TYRMAPTHTTMEN1TP53
SCHEMBL27852766 0.90 ALOX5 (0.40) TYRMAPTHTTMEN1TP53
SCHEMBL30861670 0.85 MAPT (0.36) MAPTL3MBTL1
SCHEMBL30861671 0.85 MAPT (0.36) MAPTL3MBTL1
SCHEMBL4585415 0.83 TYR (0.37) TYRMAPTMAPK10SMN1; SMN2SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101381452-A Poly(3-butylthiophen) containing function end-group and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2009-03-11 CN claimed
CN-119400861-A Composite organic electrode material, preparation method and application 湖南省正源储能材料与器件研究所 2025-02-07 CN disclosed
US-11370879-B2 Solution-processable indenofluorenes and methods to generate solution-processable indenofluorenes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-06-28 US disclosed
US-11312820-B2 Solution-processable indenofluorenes and methods to generate solution-processable indenofluorenes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-04-26 US disclosed
US-20210115187-A1 SOLUTION-PROCESSABLE INDENOFLUORENES AND METHODS TO GENERATE SOLUTION-PROCESSABLE INDENOFLUORENES INTERNATIONAL BUSINESS MACHINES CORPORATION 2021-04-22 US disclosed
US-20200190254-A1 SOLUTION-PROCESSABLE INDENOFLUORENES AND METHODS TO GENERATE SOLUTION-PROCESSABLE INDENOFLUORENES INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-06-18 US disclosed
CN-101381452-B Poly(3-butylthiophen) containing function end-group and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2011-02-16 CN disclosed
US-7838624-B2 Mixed halogen polymerization PLEXTRONICS, INC. (US) 2010-11-23 US disclosed
US-7838624-B2 Mixed halogen polymerization PLEXTRONICS, INC. (US) 2010-11-23 US disclosed
US-7838624-B2 Mixed halogen polymerization PLEXTRONICS, INC. (US) 2010-11-23 US disclosed
US-20090066233-A1 Mixed halogen polymerization PLEXTRONICS, INC. 2009-03-12 US disclosed
US-20090066233-A1 Mixed halogen polymerization PLEXTRONICS, INC. 2009-03-12 US disclosed
CN-101381452-A Poly(3-butylthiophen) containing function end-group and preparation method thereof CHANGCHUN APPLIED CHEMISTRY (CN) 2009-03-11 CN disclosed
US-20080315751-A1 Aryl-substituted conjugated polymers PLEXTRONICS, INC. 2008-12-25 US disclosed
US-20080315751-A1 Aryl-substituted conjugated polymers PLEXTRONICS, INC. 2008-12-25 US disclosed
US-20080315751-A1 Aryl-substituted conjugated polymers PLEXTRONICS, INC. 2008-12-25 US disclosed
WO-2008143838-A1 ARYL-SUBSTITUTED CONJUGATED POLYMERS PLEXTRONICS, INC. (US) 2008-11-27 WO disclosed
WO-2008143838-A1 ARYL-SUBSTITUTED CONJUGATED POLYMERS PLEXTRONICS, INC. (US) 2008-11-27 WO disclosed
WO-2008143850-A2 MIXED HALOGEN POLYMERIZATION PLEXTRONICS, INC. (US) 2008-11-27 WO disclosed
WO-2008143850-A2 MIXED HALOGEN POLYMERIZATION PLEXTRONICS, INC. (US) 2008-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370879-B2 Solution-processable indenofluorenes and methods to generate solution-processable indenofluorenes INF2, ABL1, ICMT TYR 46/4885MAPT 3729/4885L3MBTL1 4059/4885
US-11312820-B2 Solution-processable indenofluorenes and methods to generate solution-processable indenofluorenes INF2, ABL1, ICMT TYR 46/4885MAPT 3729/4885L3MBTL1 4059/4885
US-20210115187-A1 SOLUTION-PROCESSABLE INDENOFLUORENES AND METHODS TO GENERATE SOLUTION-PROCESSABLE INDENOFLUORENES INF2, ABL1, ICMT TYR 46/4885MAPT 3729/4885L3MBTL1 4059/4885
US-20200190254-A1 SOLUTION-PROCESSABLE INDENOFLUORENES AND METHODS TO GENERATE SOLUTION-PROCESSABLE INDENOFLUORENES INF2, ABL1, ICMT TYR 46/4885MAPT 3729/4885L3MBTL1 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.