SCHEMBL2872069

SCHEMBL2872069

O=COc1ccc(-c2ccccc2)c2c1-c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TDP1 Q9NUW8 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 2/20 0.35
USP2 O75604 1/20 0.35
DUSP3 P51452 1/20 0.35
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HNF4A P41235 1/20 0.33
ADRB2 P07550 2/20 0.33
ADRB1 P08588 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533468 0.81 DRD1 (0.42) ALDH1A1TDP1RAB9ASMN1; SMN2ADRB2
SCHEMBL2865511 0.79 TDP1 (0.44) ALDH1A1TDP1KMT2AKDM4ERAB9A
SCHEMBL9220620 0.77 NCOA1 (0.39) HDAC4HDAC2HDAC8HDAC6ALDH1A1
SCHEMBL2869207 0.75 HDAC4 (0.36) HDAC4HDAC2HDAC8HDAC6ALDH1A1
SCHEMBL10746370 0.74 NCOA1 (0.49) MAPTKMT2ASMN1; SMN2MAPK1HTT
SCHEMBL27412357 0.73 TOP1 (0.36) ALDH1A1TDP1MEN1MAPTKMT2A
SCHEMBL14700580 0.73 HKDC1 (0.38) ALDH1A1TDP1MEN1MAPTKMT2A
SCHEMBL17718222 0.71 MAPT (0.51) ALDH1A1TDP1MEN1MAPTKMT2A
SCHEMBL17718229 0.69 KMT2A (0.45) ALDH1A1TDP1MEN1MAPTKMT2A
SCHEMBL2874842 0.68 MAPT (0.40) ALDH1A1TDP1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100025641-A1 INFRARED REGION SELECTIVE REFLECTION COAT AND INFRARED REGION SELECTIVE REFLECTION FILM FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed