SCHEMBL2869207

SCHEMBL2869207

O=COc1c(-c2ccccc2)ccc2c1-c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
THRB P10828 1/20 0.34
XBP1 P17861 1/20 0.34
PTBP1 P26599 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
SMAD3 P84022 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872069 0.75 HDAC4 (0.36) HDAC4HDAC2HDAC8HDAC6L3MBTL1
SCHEMBL28754680 0.74 MAPT (0.39) L3MBTL1MAPTHTTNPC1RAB9A
SCHEMBL28169509 0.72 HNF4A (0.54) L3MBTL1LMNAMAPTSMN1; SMN2MEN1
SCHEMBL2865511 0.71 TDP1 (0.44) L3MBTL1LMNAHTTRAB9ASMN1; SMN2
SCHEMBL2875412 0.70 HPRT1 (0.44) L3MBTL1LMNAMAPTHTTNPC1
SCHEMBL1533468 0.69 DRD1 (0.42) L3MBTL1HTTRAB9ASMN1; SMN2TDP1
SCHEMBL27412357 0.69 TOP1 (0.36) LMNAMAPTHTTNPC1RAB9A
SCHEMBL29218008 0.68 ALDH1A1 (0.42) HDAC4HDAC2HDAC8HDAC6L3MBTL1
SCHEMBL2167186 0.67 ALDH1A1 (0.46) HDAC4HDAC2HDAC8HDAC6L3MBTL1
SCHEMBL30395776 0.67 ALDH1A1 (0.46) HDAC4HDAC2HDAC8HDAC6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945718-B1 COMPOSITION AND FILM FOR LIQUID CRYSTAL DISPLAYS FUJIFILM CORP (JP) 2010-10-20 EP disclosed
US-20090130344-A1 COMPOSITION, FILM AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2009-05-21 US disclosed
EP-1945718-A1 COMPOSITION, FILM AND LIQUID CRYSTAL DISPLAY FUJIFILM Corporation (JP) 2008-07-23 EP disclosed
WO-2007055417-A1 COMPOSITION, FILM AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2007-05-18 WO disclosed
US-20060286311-A1 Composition for nonlinear optical material, optical element, nonlinear optical material, and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2006-12-21 US disclosed