Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871839 | 0.96 | BCHE (0.40) | ATMPDPK1CCNB2PRKCBCDK1 | |
| SCHEMBL2875247 | 0.84 | METAP1 (0.34) | ACACBACACACYP3A4 | |
| SCHEMBL2876748 | 0.83 | ASAH1 (0.41) | L3MBTL1KDM4E | |
| SCHEMBL2878070 | 0.78 | HPGDS (0.46) | CYP3A4KDM4E | |
| SCHEMBL93597 | 0.76 | KDM4E (0.42) | L3MBTL1KDM4ETDP1 | |
| Thiocyanic Acid SCHEMBL1615957 | 0.70 | KDM4E (0.37) | L3MBTL1KDM4E | |
| SCHEMBL6300342 | 0.68 | STK17B (0.52) | BCHEMALT1BRD4STK17BSTK17A | |
| SCHEMBL8357911 | 0.67 | KDM4E (0.40) | L3MBTL1KDM4E | |
| SCHEMBL4422174 | 0.67 | AKT1 (0.53) | ACACBACACAAKT1CKS1BSKP1 | |
| SCHEMBL30453099 | 0.67 | AKT1 (0.53) | ACACBACACAAKT1CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043866-A2 | HISTONE LYSINE DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2010-04-22 | — | — | WO | disclosed |