Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871839 | 0.86 | BCHE (0.40) | ACACBACACA | |
| SCHEMBL2872141 | 0.84 | ATM (0.38) | ACACBACACACYP3A4 | |
| SCHEMBL2878070 | 0.80 | HPGDS (0.46) | CYP3A4 | |
| SCHEMBL93597 | 0.74 | KDM4E (0.42) | METAP1LMNAPOLB | |
| SCHEMBL2876748 | 0.72 | ASAH1 (0.41) | — | |
| SCHEMBL8235396 | 0.70 | KCNA5 (0.50) | METAP1HDAC1BRD9RXFP1LMNA | |
| SCHEMBL16523133 | 0.68 | LMNA (0.48) | METAP1HDAC1SLC29A1BRD9RXFP1 | |
| Thiocyanic Acid SCHEMBL1615957 | 0.68 | KDM4E (0.37) | METAP1LMNAPOLB | |
| SCHEMBL2872343 | 0.68 | KDM5B (0.53) | METAP1HDAC1ACACBACACALMNA | |
| SCHEMBL14907972 | 0.67 | KCNA5 (0.53) | ACACBACACASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043866-A2 | HISTONE LYSINE DEMETHYLASE INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2010-04-22 | — | — | WO | disclosed |