Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625234 | 0.78 | SNCA (0.84) | SNCANOX1MAPTLMNACYP3A4 | |
| SCHEMBL1208092 | 0.78 | SNCA (0.84) | SNCANOX1MAPTLMNACYP3A4 | |
| SCHEMBL28724407 | 0.74 | NOX1 (0.50) | SNCANOX1MAPTLMNACYP3A4 | |
| SCHEMBL30867073 | 0.72 | SNCA (0.79) | SNCANOX1MAPTCYP3A4CAPN9 | |
| SCHEMBL29214094 | 0.72 | SNCA (0.79) | SNCANOX1MAPTCYP3A4CAPN9 | |
| SCHEMBL30769632 | 0.71 | SNCA (1.00) | SNCANOX1MAPTLMNACYP3A4 | |
| SCHEMBL239724 | 0.71 | SNCA (1.00) | SNCANOX1MAPTLMNACYP3A4 | |
| SCHEMBL14571431 | 0.71 | SNCA (0.72) | SNCANOX1MAPTCYP3A4CAPN9 | |
| Dimethyl Sulfoxide SCHEMBL18398818 | 0.71 | SNCA (0.72) | SNCANOX1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL26017578 | 0.71 | SNCA (0.49) | SNCANOX1MAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340680-A | Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy | 坦博公司 | 2022-04-12 | — | — | CN | disclosed |