Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450158 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1USP2LMNAMAPT | |
| SCHEMBL28728513 | 0.78 | MAOB (0.36) | ALDH1A1LMNAGAAMCL1 | |
| SCHEMBL29467354 | 0.78 | MAOB (0.36) | ALDH1A1LMNAGAAMCL1 | |
| SCHEMBL28723299 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1USP2LMNAMAPT | |
| SCHEMBL21313335 | 0.74 | CASP1 (0.44) | KDM4EALDH1A1USP2MAPTHPGD | |
| SCHEMBL29377452 | 0.74 | CASP1 (0.44) | KDM4EALDH1A1USP2MAPTHPGD | |
| SCHEMBL29002224 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL29133923 | 0.72 | TSHR (0.46) | KDM4EALDH1A1LMNAGAAMCL1 | |
| SCHEMBL31461327 | 0.71 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP3A4GAA | |
| SCHEMBL22095321 | 0.71 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315899-A | 3- (aromatic benzimidazolyl) pyrazolopyrimidine derivative and application thereof | 上海美迪西生物医药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |