Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722480 | 0.82 | CD38 (0.37) | DGAT1MAPK1KDM4E | |
| SCHEMBL9928488 | 0.81 | DGAT1 (0.36) | MAPTDGAT1 | |
| SCHEMBL31138390 | 0.81 | DGAT1 (0.36) | MAPTDGAT1 | |
| SCHEMBL14255842 | 0.79 | ALDH1A1 (0.44) | TARBP2MAPTALDH1A1DGAT1NPC1 | |
| SCHEMBL24224456 | 0.77 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL3528543 | 0.77 | MAPT (0.43) | MAPTALDH1A1DGAT1NPC1RAB9A | |
| SCHEMBL27094264 | 0.74 | ALDH1A1 (0.38) | MAPTALDH1A1DGAT1MAPK1HSD17B10 | |
| SCHEMBL4798379 | 0.72 | ALDH1A1 (0.46) | TARBP2MAPTALDH1A1DGAT1NPC1 | |
| SCHEMBL16100174 | 0.72 | DGAT1 (0.38) | TARBP2MAPTALDH1A1DGAT1MAPK1 | |
| SCHEMBL3023087 | 0.72 | DGAT1 (0.38) | MAPTALDH1A1DGAT1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |