Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 4/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041574 | 1.00 | PHGDH (0.37) | PHGDHPIN1MMECSGALNACT1USP30 | |
| SCHEMBL23041573 | 1.00 | PHGDH (0.37) | PHGDHPIN1MMECSGALNACT1USP30 | |
| SCHEMBL23041526 | 0.94 | MME (0.37) | PHGDHPIN1MMECSGALNACT1USP30 | |
| SCHEMBL23041524 | 0.94 | MME (0.37) | PHGDHPIN1MMECSGALNACT1USP30 | |
| SCHEMBL23052261 | 0.94 | PHGDH (0.39) | PHGDHPIN1MMEUSP30HDAC3 | |
| SCHEMBL28721963 | 0.94 | PHGDH (0.39) | PHGDHPIN1MMEUSP30HDAC3 | |
| SCHEMBL23041596 | 0.94 | PHGDH (0.39) | PHGDHPIN1MMEUSP30HDAC3 | |
| SCHEMBL23052257 | 0.94 | PHGDH (0.39) | PHGDHPIN1MMEUSP30HDAC3 | |
| SCHEMBL23052279 | 0.91 | ALDH1A1 (0.34) | PHGDH | |
| SCHEMBL29452671 | 0.91 | ALDH1A1 (0.34) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |