Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 3/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452671 | 1.00 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDFAAHSMN1; SMN2 | |
| SCHEMBL23052223 | 0.94 | FAAH (0.34) | ALDH1A1KDM4EFAAHSMN1; SMN2PHGDH | |
| SCHEMBL29452755 | 0.94 | FAAH (0.34) | ALDH1A1KDM4EFAAHSMN1; SMN2PHGDH | |
| SCHEMBL28722574 | 0.91 | PHGDH (0.37) | PHGDH | |
| SCHEMBL23041573 | 0.91 | PHGDH (0.37) | PHGDH | |
| SCHEMBL23041574 | 0.91 | PHGDH (0.37) | PHGDH | |
| SCHEMBL23052261 | 0.91 | PHGDH (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL23041596 | 0.91 | PHGDH (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL23052257 | 0.91 | PHGDH (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL28721963 | 0.91 | PHGDH (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |