Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481816 | 1.00 | RAB9A (0.41) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL28724732 | 1.00 | RAB9A (0.41) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29481771 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6983957 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6983952 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29444768 | 0.89 | ALDH1A1 (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10188107 | 0.82 | RAB9A (0.52) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL15337638 | 0.76 | RAB9A (0.42) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL12180345 | 0.75 | RAB9A (0.62) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL27863302 | 0.74 | ALDH1A1 (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | disclosed |