Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.67 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956913 | 0.87 | GPR119 (0.68) | GPR119GPR183CNR2KCNH2LMNA | |
| SCHEMBL6118208 | 0.85 | GPR119 (0.67) | GPR119GPR183CNR2KCNH2LMNA | |
| SCHEMBL387876 | 0.85 | GPR119 (0.71) | GPR119GPR183CNR2KCNH2LMNA | |
| SCHEMBL5779093 | 0.84 | GPR119 (0.74) | GPR119GPR183CNR2LMNAMAPT | |
| SCHEMBL19450515 | 0.84 | GPR119 (0.65) | GPR119GPR183CNR2KCNH2 | |
| SCHEMBL1922450 | 0.84 | GPR119 (0.65) | GPR119GPR183CNR2KCNH2 | |
| SCHEMBL22514057 | 0.83 | GPR119 (0.63) | GPR119GPR183CNR2KCNH2LMNA | |
| SCHEMBL19454550 | 0.83 | GPR119 (0.68) | GPR119GPR183CNR2KCNH2 | |
| SCHEMBL18843833 | 0.83 | GPR119 (0.63) | GPR119GPR183CNR2KCNH2LMNA | |
| SCHEMBL21665285 | 0.82 | GPR119 (0.62) | GPR119GPR183CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415381-B | Thiazolopyridine derivatives as GPR119 agonists | 人类制药有限公司 | 2022-03-25 | — | — | CN | disclosed |