Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.38 |
| ▸ | HTR1B | P28222 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555954 | 0.86 | GRM1 (0.43) | CCNT1CDK9 | |
| SCHEMBL19838659 | 0.86 | GRM1 (0.43) | CCNT1CDK9 | |
| SCHEMBL21967952 | 0.80 | HTR1D (0.55) | HTR1DHTR1BMAPTMEN1KMT2A | |
| SCHEMBL28433354 | 0.73 | BTK (0.37) | HTR1DHTR1BMAPTMEN1KMT2A | |
| SCHEMBL28725598 | 0.73 | HTR1D (0.56) | HTR1DHTR1BKMT2AALOX15HSD17B10 | |
| SCHEMBL25223587 | 0.71 | HTR1D (0.51) | HTR1DHTR1BMAPTMEN1KMT2A | |
| SCHEMBL16422318 | 0.70 | QDPR (0.51) | MAPTMEN1KMT2ALMNAQDPR | |
| SCHEMBL28725580 | 0.70 | HTR1D (0.52) | HTR1DHTR1BMAPTMEN1KMT2A | |
| SCHEMBL28725616 | 0.69 | HTR1D (0.59) | HTR1DHTR1B | |
| SCHEMBL15174850 | 0.69 | QDPR (0.49) | MAPTMEN1KMT2AQDPRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448190-B | Substituted indole compounds | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-109715617-B | Dimethoxyphenyl-substituted indole compounds as inhibitors of TLR7, TLR8 or TLR9 | 百时美施贵宝公司 | 2022-04-19 | — | — | CN | disclosed |