Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30293083 | 0.86 | CDK9 (0.44) | CCNT1CDK9 | |
| SCHEMBL22438309 | 0.86 | CDK9 (0.44) | CCNT1CDK9 | |
| SCHEMBL6364678 | 0.74 | BTK (0.41) | BTKMAPTMEN1LMNAKMT2A | |
| SCHEMBL28725841 | 0.73 | HTR1D (0.38) | MAPTTP53MEN1LMNAKMT2A | |
| SCHEMBL21967952 | 0.73 | HTR1D (0.55) | MAPTMEN1LMNAKMT2AHTR1D | |
| SCHEMBL29221512 | 0.72 | BTK (0.40) | BTKMAPTMEN1LMNAKMT2A | |
| SCHEMBL22491445 | 0.68 | MAPT (0.56) | MAPTLMNA | |
| SCHEMBL28725598 | 0.68 | HTR1D (0.56) | KMT2AHTR1DHTR1B | |
| SCHEMBL28971538 | 0.67 | ALDH1A1 (0.46) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL23644920 | 0.66 | SLC6A4 (0.37) | MAPTTP53MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448190-A | Substituted indole compounds | 百时美施贵宝公司 | 2020-07-24 | — | — | CN | disclosed |