Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15117450 | 0.74 | BACE1 (0.36) | MAPK14IP6K1MAPT | |
| SCHEMBL15147860 | 0.74 | CRBN (0.40) | CRBNMAPK1PARP1ALDH1A1PTGER4 | |
| SCHEMBL29879054 | 0.74 | CRBN (0.40) | CRBNMAPK1PARP1ALDH1A1PTGER4 | |
| SCHEMBL5310756 | 0.72 | CRBN (0.44) | CRBNMAPK1PARP1 | |
| SCHEMBL24306815 | 0.72 | CRBN (0.36) | CRBNMAPK1PARP1ALDH1A1 | |
| SCHEMBL22711631 | 0.70 | IP6K1 (0.44) | CRBNMAPK1PARP1IP6K1 | |
| SCHEMBL17436137 | 0.70 | PGR (0.38) | MAPK14MAP3K11 | |
| SCHEMBL21034342 | 0.70 | MAPK1 (0.37) | MAPK1ALDH1A1PTGER4CYP1A2GAA | |
| SCHEMBL31411757 | 0.70 | MAPK14 (0.50) | MAPK14IP6K1ALDH1A1CYP1A2 | |
| SCHEMBL30681131 | 0.69 | IP6K1 (0.49) | MAPK14CRBNPARP1IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745321-B | Pharmaceutical composition comprising FGFR4 inhibitor | 上海翰森生物医药科技有限公司 | 2022-04-29 | — | — | CN | disclosed |