Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728469 | 0.85 | SLC15A1 (0.42) | SLC15A1LTA4H | |
| SCHEMBL28805500 | 0.82 | SLC15A1 (0.45) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL28805499 | 0.82 | SLC15A1 (0.45) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL27899925 | 0.80 | ABCB1 (0.44) | SLC15A1MEN1KMT2AALDH1A1LTA4H | |
| SCHEMBL11301781 | 0.78 | SLC15A1 (0.42) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL9131026 | 0.78 | ALDH1A1 (0.43) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL9229566 | 0.76 | SLC15A1 (0.38) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL27418628 | 0.76 | SLC15A1 (0.52) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7794341 | 0.76 | SLC15A1 (0.52) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL15263132 | 0.76 | SLC15A1 (0.47) | SLC15A1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409562-B | CA4 derivative and ligand-drug conjugate thereof | 四川百利药业有限责任公司 | 2024-08-02 | — | — | CN | disclosed |
| WO-2022166719-A1 | CA4 DERIVATIVE AND LIGAND-DRUG CONJUGATE THEREOF | 四川百利药业有限责任公司 | 2022-08-11 | — | — | WO | disclosed |
| CN-114409562-A | CA4 derivative and ligand-drug conjugate thereof | 四川百利药业有限责任公司 | 2022-04-29 | — | — | CN | disclosed |