Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467455 | 1.00 | KMT2A (0.41) | KMT2AMEN1QPCTQPCTLCYP1A2 | |
| SCHEMBL29467466 | 0.76 | MEN1 (0.34) | KMT2AMEN1QPCTQPCTLCYP1A2 | |
| SCHEMBL28728600 | 0.76 | MEN1 (0.34) | KMT2AMEN1QPCTQPCTLCYP1A2 | |
| SCHEMBL561513 | 0.72 | GRM2 (0.43) | MTORPIK3CABCDIN3D | |
| SCHEMBL22869317 | 0.71 | QPCT (0.40) | QPCTQPCTLCYP1A2METAP2MTOR | |
| SCHEMBL29565225 | 0.71 | QPCT (0.40) | QPCTQPCTLCYP1A2METAP2MTOR | |
| SCHEMBL560718 | 0.71 | ACVR2A (0.43) | — | |
| SCHEMBL30701718 | 0.70 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2MTOR | |
| SCHEMBL27191340 | 0.70 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2HSD11B1 | |
| SCHEMBL27191366 | 0.70 | QPCT (0.41) | QPCTQPCTLCYP1A2METAP2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315839-A | Pyrimidinedione compounds and use thereof | 武汉人福创新药物研发中心有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2022068929-A1 | PYRIMIDINEDIONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-04-07 | — | — | WO | disclosed |