Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28500637 | 0.77 | CYP19A1 (0.42) | MAPTKDM4EACHECYP19A1DRD2 | |
| SCHEMBL28501373 | 0.75 | CYP19A1 (0.47) | ACHECYP19A1DRD2DRD3 | |
| SCHEMBL5275161 | 0.74 | ACHE (0.73) | MAPTKDM4ELMNAPOLBACHE | |
| SCHEMBL6957074 | 0.73 | MAPT (0.59) | MAPTKDM4ELMNAPOLBACHE | |
| Hydrochloric Acid SCHEMBL7272487 | 0.72 | KDM4E (0.58) | MAPTKDM4ELMNAPOLBACHE | |
| SCHEMBL7517153 | 0.72 | MAPT (0.58) | MAPTKDM4ELMNAPOLBACHE | |
| SCHEMBL28507112 | 0.71 | ACHE (0.43) | ACHEDRD2 | |
| SCHEMBL15700133 | 0.70 | CYP19A1 (0.67) | MAPTKDM4ELMNAPOLBACHE | |
| SCHEMBL28507951 | 0.70 | ACHE (0.43) | KDM4EACHEALDH1A1CYP3A4 | |
| SCHEMBL9361537 | 0.69 | MAPT (0.59) | MAPTKDM4ELMNAPOLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003187-B | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2021-11-05 | — | — | CN | claimed |
| CN-110003187-A | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2019-07-12 | — | — | CN | claimed |
| CN-110003187-B | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2021-11-05 | — | — | CN | disclosed |