Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HCK | P08631 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828888 | 0.78 | NPC1 (0.50) | KMT2ALMNANPC1RAB9ALTA4H | |
| SCHEMBL21777399 | 0.77 | KMT2A (0.66) | KMT2ALMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3232677 | 0.74 | NPC1 (0.49) | KMT2ALMNANPC1RAB9ALTA4H | |
| SCHEMBL401804 | 0.74 | NPC1 (0.52) | KMT2ALMNANPC1RAB9ALTA4H | |
| SCHEMBL18609314 | 0.74 | LMNA (0.54) | LMNANPC1RAB9ALTA4HCYP2D6 | |
| SCHEMBL8267758 | 0.74 | NPC1 (0.56) | KMT2ALMNANPC1RAB9ALTA4H | |
| SCHEMBL4413921 | 0.74 | RAB9A (0.55) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18590275 | 0.73 | NPC1 (0.48) | LMNANPC1RAB9ALTA4HCYP2D6 | |
| SCHEMBL23709510 | 0.72 | NPC1 (0.47) | LMNANPC1RAB9ALTA4HCYP2D6 | |
| SCHEMBL7919192 | 0.72 | SMN1; SMN2 (0.60) | LMNANPC1RAB9ALTA4HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613652-A | Benzimidazole compounds and their use for treating alzheimer's disease or huntington's disease | 台湾卫生研究院 | 2021-11-05 | — | — | CN | disclosed |