Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24486590 | 1.00 | CTSL (0.53) | CTSLCTSB | |
| SCHEMBL19605974 | 1.00 | CTSL (0.53) | CTSLCTSB | |
| SCHEMBL24690762 | 1.00 | CTSL (0.53) | CTSLCTSB | |
| SCHEMBL19605949 | 0.94 | CTSL (0.48) | CTSLCTSB | |
| SCHEMBL22758585 | 0.94 | CTSL (0.48) | CTSLCTSB | |
| SCHEMBL19586866 | 0.91 | CTSL (0.54) | CTSLCTSB | |
| SCHEMBL19586870 | 0.91 | CTSL (0.54) | CTSLCTSB | |
| SCHEMBL19586868 | 0.91 | CTSL (0.54) | CTSLCTSB | |
| SCHEMBL14838051 | 0.91 | NFKB1 (0.43) | — | |
| SCHEMBL23782042 | 0.91 | NFKB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114681443-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2024-05-10 | — | — | CN | disclosed |
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114466838-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-05-02 | — | — | CN | disclosed |
| CN-114681443-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-07-01 | — | — | CN | disclosed |
| CN-114466838-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2022-05-10 | — | — | CN | disclosed |