Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620896 | 0.80 | TRPV1 (0.52) | TRPV1HDAC1HDAC6DGAT1ALOX5 | |
| SCHEMBL29620901 | 0.75 | TRPV1 (0.54) | TRPV1ALOX5FLT1KDRVCP | |
| SCHEMBL22925839 | 0.75 | KMT2A (0.52) | TRPV1DGAT1ALOX5FLT1KDR | |
| SCHEMBL22925556 | 0.74 | TRPV1 (0.55) | TRPV1DGAT1ALOX5FLT1KDR | |
| SCHEMBL31013395 | 0.73 | TRPV1 (0.58) | TRPV1HDAC1HDAC6DGAT1FLT1 | |
| SCHEMBL28733726 | 0.72 | TRPV1 (0.52) | TRPV1HDAC1HDAC6DGAT1ALOX5 | |
| SCHEMBL23540014 | 0.72 | VCP (0.69) | TRPV1ALOX5FLT1KDRPRKAB2 | |
| SCHEMBL29620938 | 0.72 | TRPV1 (0.48) | TRPV1HDAC1HDAC6DGAT1ALOX5 | |
| SCHEMBL22925571 | 0.71 | TRPV1 (0.49) | TRPV1DGAT1ALOX5FLT1KDR | |
| SCHEMBL22925673 | 0.70 | TRPV1 (0.59) | TRPV1ALOX5FLT1KDRVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |