Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 3/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620901 | 0.85 | TRPV1 (0.54) | TRPV1ALOX5VCPKITKDR | |
| SCHEMBL28733745 | 0.80 | TRPV1 (0.47) | TRPV1ALOX5VCPHDAC1HDAC6 | |
| SCHEMBL23540014 | 0.77 | VCP (0.69) | TRPV1ALOX5VCPKDRFLT1 | |
| SCHEMBL22925556 | 0.77 | TRPV1 (0.55) | TRPV1ALOX5VCPKITDGAT1 | |
| SCHEMBL22925673 | 0.75 | TRPV1 (0.59) | TRPV1ALOX5VCPKDRFLT1 | |
| SCHEMBL14057525 | 0.73 | TRPV1 (0.66) | TRPV1ALOX5VCPKDRFLT1 | |
| SCHEMBL26307279 | 0.72 | FLT1 (0.52) | TRPV1ALOX5VCPKDRFLT1 | |
| SCHEMBL23540651 | 0.72 | VCP (0.69) | TRPV1ALOX5VCPKDRFLT1 | |
| SCHEMBL22925566 | 0.71 | TRPV1 (0.47) | TRPV1ALOX5VCPHDAC1HDAC6 | |
| SCHEMBL22925553 | 0.71 | TRPV1 (0.49) | TRPV1ALOX5VCPHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |