Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259383 | 0.83 | CASP3 (0.57) | CASP3SCN10ACHRNA7MAPTDPP4 | |
| SCHEMBL29620888 | 0.81 | GRM5 (0.45) | CASP3NOTUMCHRNA7 | |
| SCHEMBL28733657 | 0.81 | GRM5 (0.45) | CASP3NOTUMCHRNA7 | |
| SCHEMBL22925912 | 0.80 | NOTUM (0.61) | CASP3NOTUMS1PR1 | |
| SCHEMBL18105085 | 0.79 | CASP3 (0.53) | CASP3SCN10ACHRNA7MAPTPKM | |
| SCHEMBL1114128 | 0.78 | SCN10A (0.61) | CASP3SCN10ACHRNA7MAPTPKM | |
| SCHEMBL16088931 | 0.78 | DPP4 (0.61) | CASP3SCN10ACHRNA7MAPTDPP4 | |
| SCHEMBL22897781 | 0.78 | CASP3 (0.52) | CASP3SCN10AMAPTDPP4S1PR1 | |
| SCHEMBL15498668 | 0.78 | SCN10A (0.67) | CASP3SCN10AMAPTPKMXBP1 | |
| SCHEMBL203702 | 0.77 | S1PR1 (0.55) | CASP3SCN10AMAPTPKMXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-B | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |