Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16262930 | 0.90 | MAPT (0.50) | QDPRLMNATSHRTDP1MAPT | |
| SCHEMBL16262927 | 0.90 | MAPT (0.50) | QDPRLMNATSHRTDP1MAPT | |
| SCHEMBL17398284 | 0.85 | QDPR (0.47) | QDPRLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL17398277 | 0.85 | QDPR (0.47) | QDPRLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL27037449 | 0.84 | QDPR (0.54) | QDPRMAPK1TSHRMAPTALDH1A1 | |
| SCHEMBL30778322 | 0.83 | NAMPT (0.50) | QDPRLMNAMAPTALDH1A1 | |
| SCHEMBL29656809 | 0.83 | NAMPT (0.50) | QDPRLMNAMAPTALDH1A1 | |
| SCHEMBL16262849 | 0.83 | QDPR (0.51) | QDPRLMNATSHRMAPTALDH1A1 | |
| SCHEMBL3986414 | 0.83 | QDPR (0.44) | QDPRLMNATSHRMAPTALDH1A1 | |
| SCHEMBL3986410 | 0.83 | QDPR (0.44) | QDPRLMNATSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460732-A | Pyrrolopyridone compounds, preparation method and application thereof | 杭州中美华东制药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-109721620-B | HPK1 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |