Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | CFD | P00746 | 5/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.40 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219236 | 0.86 | CFTR (0.45) | NHERF1CFTR | |
| SCHEMBL29852931 | 0.86 | CFTR (0.45) | NHERF1CFTR | |
| SCHEMBL29592746 | 0.78 | CFD (0.67) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL23219169 | 0.78 | CFD (0.67) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL5480973 | 0.77 | CFTR (0.64) | NHERF1CFTRNR1H4 | |
| SCHEMBL23195348 | 0.72 | F7 (0.44) | ADORA2A | |
| SCHEMBL29592699 | 0.72 | F7 (0.44) | ADORA2A | |
| SCHEMBL14855928 | 0.70 | NR1H4 (0.66) | NR1H4CFDSUCNR1BCAT2F11 | |
| SCHEMBL30390687 | 0.69 | STING1 (0.34) | ADORA2AKDR | |
| SCHEMBL26658318 | 0.69 | STING1 (0.34) | ADORA2AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |