Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941708 | 0.87 | AR (0.54) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL9590802 | 0.84 | AR (0.51) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL9589393 | 0.84 | AR (0.51) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL9589073 | 0.83 | AR (0.53) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL5818265 | 0.80 | RXFP1 (0.50) | MAPTNPSR1THRATHRBALDH1A1 | |
| SCHEMBL1028223 | 0.78 | POLB (0.48) | L3MBTL1MAPTALDH1A1POLBKDM4E | |
| SCHEMBL12732731 | 0.78 | NPSR1 (0.50) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL15392450 | 0.78 | L3MBTL1 (0.49) | L3MBTL1MAPTNPSR1F10TEAD1 | |
| SCHEMBL19563690 | 0.78 | L3MBTL1 (0.56) | L3MBTL1MAPTNPSR1GCGRALDH1A1 | |
| SCHEMBL9798371 | 0.77 | LTA4H (0.54) | L3MBTL1MAPTNPSR1TEAD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502540-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2022-05-13 | — | — | CN | disclosed |