Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 14/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873805 | 1.00 | ICMT (0.46) | ICMTPOLBALDH1A1MAPTATM | |
| SCHEMBL2874018 | 0.92 | ICMT (0.46) | ICMTPOLBALDH1A1MAPT | |
| SCHEMBL2872660 | 0.90 | ICMT (0.47) | ICMTALDH1A1MAPT | |
| SCHEMBL2872657 | 0.90 | ICMT (0.47) | ICMTALDH1A1MAPT | |
| SCHEMBL2878036 | 0.90 | ICMT (0.55) | ICMTPOLBALDH1A1MAPT | |
| SCHEMBL2878038 | 0.90 | ICMT (0.55) | ICMTPOLBALDH1A1MAPT | |
| SCHEMBL2871971 | 0.82 | ICMT (0.41) | ICMTALDH1A1MAPT | |
| SCHEMBL2880095 | 0.80 | ICMT (0.51) | ICMTALDH1A1MAPT | |
| SCHEMBL2877690 | 0.79 | ICMT (0.45) | ICMTPOLBALDH1A1MAPT | |
| SCHEMBL2877689 | 0.79 | ICMT (0.45) | ICMTPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745589-B1 | Antibodies and unnatural substrates of prenylation enzymes for use in detecting and isolating prenylated proteins | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |