Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 14/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877690 | 1.00 | ICMT (0.45) | ICMTMAPTALDH1A1TRPA1GMNN | |
| SCHEMBL2877315 | 0.86 | ICMT (0.45) | ICMTMAPTALDH1A1 | |
| SCHEMBL2877316 | 0.86 | ICMT (0.45) | ICMTMAPTALDH1A1 | |
| SCHEMBL2872660 | 0.82 | ICMT (0.47) | ICMTMAPTALDH1A1 | |
| SCHEMBL2872657 | 0.82 | ICMT (0.47) | ICMTMAPTALDH1A1 | |
| SCHEMBL8977916 | 0.81 | MAPT (0.57) | ICMTMAPTALDH1A1TRPA1MEN1 | |
| SCHEMBL14596316 | 0.81 | MAPT (0.57) | ICMTMAPTALDH1A1TRPA1MEN1 | |
| SCHEMBL2880044 | 0.81 | MAPT (0.57) | ICMTMAPTALDH1A1TRPA1MEN1 | |
| SCHEMBL14663234 | 0.81 | MAPT (0.57) | ICMTMAPTALDH1A1TRPA1MEN1 | |
| SCHEMBL8977914 | 0.81 | MAPT (0.57) | ICMTMAPTALDH1A1TRPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745589-B1 | Antibodies and unnatural substrates of prenylation enzymes for use in detecting and isolating prenylated proteins | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |