Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.62 |
| ▸ | AGXT | P21549 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.49 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425007 | 0.98 | ITGB3 (0.64) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL17890851 | 0.85 | AGXT (0.57) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL5790195 | 0.85 | AGXT (0.61) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL16880373 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BAGXTNPC1RAB9A | |
| SCHEMBL23256404 | 0.84 | ITGB3 (0.61) | ITGB3ITGA2B | |
| SCHEMBL5790197 | 0.83 | AGXT (0.61) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL29589898 | 0.83 | AGXT (0.58) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL15710135 | 0.83 | AGXT (0.58) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL17420453 | 0.81 | AGXT (0.56) | ITGB3ITGA2BAGXTADRA2CNPC1 | |
| SCHEMBL6583384 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2BAGXTADRA2CPLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |