Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.61 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425007 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL23256405 | 0.85 | SMN1; SMN2 (0.57) | ITGB3ITGA2BGFERUSP2SMN1; SMN2 | |
| SCHEMBL28739636 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2B | |
| SCHEMBL16880373 | 0.83 | ITGB3 (0.64) | ITGB3ITGA2BUSP2SMN1; SMN2HSD17B10 | |
| SCHEMBL20424995 | 0.82 | GFER (0.61) | ITGB3ITGA2BGFERSMN1; SMN2MAPK1 | |
| SCHEMBL23643941 | 0.82 | GPR119 (0.55) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9011030 | 0.80 | USP2 (0.71) | ITGB3ITGA2BGFERUSP2SMN1; SMN2 | |
| SCHEMBL23256393 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BUSP2CYP1A2CYP2D6 | |
| SCHEMBL6583384 | 0.79 | ITGB3 (0.64) | ITGB3ITGA2BSMN1; SMN2MAPTMEN1 | |
| SCHEMBL2069326 | 0.79 | AOC3 (0.69) | GFERMAPK1GAAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573961-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2023-10-25 | — | — | EP | disclosed |
| US-10987351-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-04-27 | — | — | US | disclosed |
| US-10987351-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | ITGB3 1439/4885ITGA2B 862/4885GFER 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.