Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235719 | 0.84 | CHRM2 (0.37) | KMT2AKDM4EMAPTPPARGPPARA | |
| SCHEMBL28655594 | 0.78 | L3MBTL1 (0.42) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| SCHEMBL28749714 | 0.75 | MEN1 (0.48) | L3MBTL1PKMALDH1A1KMT2AMAPT | |
| SCHEMBL19968757 | 0.73 | HTR2C (0.46) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| SCHEMBL24058148 | 0.72 | IDO1 (0.43) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| SCHEMBL30024860 | 0.72 | IDO1 (0.43) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| Ethylbenzene SCHEMBL27571280 | 0.72 | TP53 (0.50) | ALDH1A1KMT2AMAPTPPARGPPARA | |
| SCHEMBL17010335 | 0.71 | ALDH1A1 (0.50) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| SCHEMBL27511261 | 0.71 | POLB (0.46) | L3MBTL1PKMALDH1A1CYP2C9KMT2A | |
| SCHEMBL24058160 | 0.69 | POLB (0.53) | L3MBTL1PKMALDH1A1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1206231-C | 7-acylamino-3-heteroarylthio-3-cephem carboxylic and prodrugs thereof | BASIC THERAPY INC (US) | 2005-06-15 | — | — | CN | disclosed |
| CN-1451011-A | 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof | BASIC THERAPY INC (US) | 2003-10-22 | — | — | CN | disclosed |