Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741983 | 0.90 | CBLB (0.49) | CBLBMEN1KMT2AATM | |
| SCHEMBL28741805 | 0.82 | MEN1 (0.40) | CBLBMEN1KMT2AATMPRSS1 | |
| SCHEMBL21201152 | 0.77 | CBLB (0.55) | CBLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL22944950 | 0.76 | CBLB (0.52) | CBLB | |
| SCHEMBL29640156 | 0.76 | CBLB (0.52) | CBLB | |
| SCHEMBL28741906 | 0.71 | KDM4E (0.49) | MEN1KMT2AATMPRSS1ACR | |
| SCHEMBL21201280 | 0.70 | CBLB (0.44) | CBLB | |
| SCHEMBL29920925 | 0.70 | MEN1 (0.66) | MEN1KMT2AATMPRSS1ACR | |
| SCHEMBL80101 | 0.70 | MEN1 (0.66) | MEN1KMT2APRSS1ACRLMNA | |
| SCHEMBL27823092 | 0.70 | MEN1 (0.66) | MEN1KMT2AATMPRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |