Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791807 | 0.90 | ALDH1A1 (0.57) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL27559441 | 0.88 | CYP2D6 (0.52) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL27512822 | 0.88 | MAPK1 (0.49) | KMT2AALDH1A1MAPK1HRH3CYP1A2 | |
| SCHEMBL7786125 | 0.86 | MAPK1 (0.51) | ALDH1A1MAPK1HRH3CYP1A2CHRM2 | |
| SCHEMBL27495200 | 0.85 | TSHR (0.45) | ALDH1A1HRH3TSHRCYP2D6USP2 | |
| SCHEMBL27495577 | 0.85 | ALDH1A1 (0.47) | MAPTCHRNA7KMT2AALDH1A1MAPK1 | |
| SCHEMBL7792554 | 0.84 | MAPT (0.67) | MAPTCHRNA7KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27493583 | 0.84 | USP2 (0.45) | KMT2AALDH1A1MAPK1HRH3CYP1A2 | |
| SCHEMBL7786133 | 0.83 | ALDH1A1 (0.58) | MAPTKMT2AALDH1A1MAPK1HRH3 | |
| SCHEMBL27512147 | 0.83 | MAPT (0.47) | MAPTCHRNA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235969-A | Intermediates used in preparing dihydrobenzolfuran derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-11-24 | — | — | CN | disclosed |
| CN-1220660-A | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-23 | — | — | CN | disclosed |