Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630080 | 0.89 | GRIN2B (0.38) | CYP4F2CYP4A11HPGDJAK3GRIN2B | |
| SCHEMBL6642949 | 0.83 | HPGD (0.36) | CYP4F2CYP4A11HPGDJAK3GRIN2B | |
| SCHEMBL8129886 | 0.80 | GRIN2B (0.40) | HPGDJAK3GRIN2BGRIN2CCTSK | |
| SCHEMBL1963765 | 0.80 | GRIN2B (0.32) | CYP4F2CYP4A11GRIN2BGRIN2C | |
| SCHEMBL8484892 | 0.79 | JAK3 (0.33) | CYP4F2CYP4A11HPGDJAK3GRIN2B | |
| SCHEMBL28779766 | 0.79 | GRIN2B (0.36) | CYP4F2CYP4A11GRIN2BGRIN2CCTSK | |
| SCHEMBL28743535 | 0.78 | CYP2C19 (0.32) | — | |
| SCHEMBL30244734 | 0.77 | HPGD (0.33) | CYP4F2CYP4A11HPGDCTSKUSP2 | |
| SCHEMBL8585741 | 0.77 | HPGD (0.33) | CYP4F2CYP4A11HPGDCTSKUSP2 | |
| SCHEMBL2216266 | 0.77 | HPGD (0.33) | CYP4F2CYP4A11HPGDCTSKUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330353-B1 | TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0330353-A1 | Tetrazole excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |