SCHEMBL1966290

SCHEMBL1966290

O=C(O)N1CCCCC1(O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1966761 0.93
SCHEMBL28743535 0.77 CYP2C19 (0.32) CYP2C19MEN1KMT2A
SCHEMBL28236926 0.77 MEN1 (0.32) MEN1KMT2A
SCHEMBL3810212 0.77
SCHEMBL3882899 0.77 CYP3A4 (0.36)
SCHEMBL468846 0.77 CYP3A4 (0.36)
SCHEMBL940715 0.76 CYP2C19 (0.31) CYP2C19MEN1KMT2A
SCHEMBL3578695 0.76 CYP2C19 (0.31) CYP2C19MEN1KMT2A
SCHEMBL23525345 0.74 FFAR3 (0.32) CYP2C19MEN1KMT2A
SCHEMBL3430843 0.74 MEN1 (0.30) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114514023-A Methods of treating pancreatic cancer using RAD51 inhibitors 赛泰尔治疗公司 2022-05-17 CN disclosed
EP-2334677-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS Array Biopharma, Inc. (US) 2011-06-22 EP disclosed
WO-2010022076-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2010-02-25 WO disclosed
EP-1856095-A1 QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS AstraZeneca AB (SE) 2007-11-21 EP disclosed
WO-2006090163-A1 QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS ASTRAZENECA AB (SE) 2006-08-31 WO disclosed