Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27503313 | 0.81 | CYP17A1 (0.60) | KDM4EMAPK1HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL13804249 | 0.78 | ERN1 (0.47) | ERN1EGFRKDRCYP17A1CYP11B1 | |
| SCHEMBL642228 | 0.77 | HDAC4 (0.58) | ERN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29788008 | 0.75 | HDAC4 (0.53) | ERN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL4579619 | 0.75 | HDAC4 (0.53) | ERN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6754272 | 0.73 | CYP1A2 (0.54) | ERN1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8502557 | 0.73 | CYP17A1 (0.55) | ERN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3674074 | 0.72 | CA9 (0.50) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL30701949 | 0.72 | CA9 (0.50) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7260001 | 0.72 | ERN1 (0.49) | ERN1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491352-C | Asymmetrical cyclic diamine compound | KOWA CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1242992-C | Cyclic diamine compounds bearing six-membered cyclic groups | KOWA CO (JP) | 2006-02-22 | — | — | CN | disclosed |
| CN-1520402-A | Unsymmetrical cyclic diamine compound | ������������ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1520400-A | Cyclic diamine compounds with six-membered cyclic groups | ������������ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |