SCHEMBL13804249

SCHEMBL13804249

COc1ccc(-c2cncnc2)c2c(OC)c(-c3cc(-c4cncnc4)c4c(OC)ccc(-c5cncnc5)c4c3OC)cc(-c3cncnc3)c12

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.47
EGFR P00533 1/20 0.42
KDR P35968 1/20 0.42
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
AAK1 Q2M2I8 1/20 0.38
CHEK1 O14757 1/20 0.36
KCNH2 Q12809 2/20 0.36
ABL1 P00519 1/20 0.36
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13781461 0.85 CYP11B1 (0.52) ERN1EGFRKDRCYP17A1CYP11B1
SCHEMBL13781462 0.82 CYP11B1 (0.49) ERN1EGFRKDRCYP17A1CYP11B1
SCHEMBL13781463 0.81 NPC1 (0.41)
SCHEMBL28743751 0.78 ERN1 (0.53) ERN1EGFRKDRCYP17A1CYP11B1
SCHEMBL13781465 0.78 TUBB4A (0.46) EGFRKDRCYP17A1CYP11B1CYP11B2
SCHEMBL13781459 0.78 TUBB4A (0.46) EGFRKDRCYP17A1CYP11B1CYP11B2
SCHEMBL13781460 0.78 TUBB4A (0.46) EGFRKDRCYP17A1CYP11B1CYP11B2
SCHEMBL13781464 0.76 ALDH1A1 (0.49) KDRCHEK1ABL1
SCHEMBL13781458 0.76 TDO2 (0.44) EGFR
SCHEMBL13781467 0.73 ALDH1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090160315-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELEMENT USING THE SAME YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2009-06-25 US disclosed
US-20090160315-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELEMENT USING THE SAME YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090160315-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ELEMENT USING THE SAME RPL19, L1CAM, ELAVL1 ERN1 1141/4885EGFR 637/4885KDR 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.