Ciproquazone

Ciproquazone

SCHEMBL287449

COc1ccc2c(c1)c(-c1ccccc1)nc(=O)n2CC1CC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CASR P41180 8/20 0.58
PTGER4 P35408 1/20 0.48
PTGIR P43119 1/20 0.48
GRIK2 Q13002 1/20 0.45
LMNA P02545 2/20 0.44
PLA2G2A P14555 1/20 0.44
TP53 P04637 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11163140 0.93 CASR (0.56) CASRPTGER4PTGIRGRIK2PLA2G2A
SCHEMBL11162244 0.91 CASR (0.50) CASRPTGER4PTGIRTP53GRIN1
SCHEMBL11865298 0.90 CASR (0.50) CASRPTGER4PTGIRPLA2G2ANPSR1
SCHEMBL11168842 0.87 CASR (0.47) CASRPTGER4PTGIRGRIK2PLA2G2A
SCHEMBL11156687 0.86 CASR (0.49) CASRPTGER4PLA2G2AGRIN1GRIN2B
SCHEMBL11864694 0.85 MAPT (0.44) CASRPTGER4PLA2G2ATP53KDM4E
SCHEMBL11635741 0.85 NR1I2 (0.49) PTGER4PTGIRLMNATP53KDM4E
SCHEMBL11636514 0.85 CASR (0.49) CASRPTGER4PTGIRLMNATP53
SCHEMBL11462576 0.83 CASR (0.59) CASRGRIK2LMNATP53KDM4E
SCHEMBL11156465 0.83 GRIN1 (0.42) CASRPTGER4PLA2G2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-4442084-A ABSORPTION, LIQUID PHASE CLAUS PROCESS, RECYCLING SANDOZ LTD. (CH) 1984-04-10 US claimed
US-4247554-A ADMINISTERING A QUINAZOLINONE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-27 US claimed
US-20250304667-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2025-10-02 US disclosed
EP-3693381-B1 LIGAND BINDING MOLECULES AND USES THEREOF VEGENICS PTY LTD (AU) 2025-09-03 EP disclosed
US-20250161402-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE SCHEPENS EYE RES INST (US) 2025-05-22 US disclosed
CN-116172005-B Weeding composition containing saflufenacil and application thereof 江苏瑞邦农化股份有限公司 2025-04-25 CN disclosed
CN-116420730-B Water-emulsifiable paste for preventing and removing resistant gramineous weeds in paddy field and preparation method thereof 浙江天丰生物科学有限公司 2025-03-14 CN disclosed
CN-114794133-B Weeding composition containing sulfenamide and application thereof 江苏瑞邦农化股份有限公司 2024-10-15 CN disclosed
US-4395550-A Tetrahydro-2(1H)-quinazolinones and cyclohexene nitriles SANDOZ LTD. (CH) 1983-07-26 US disclosed
US-4387223-A Process for preparing 2(1H)-quinazolinone derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-06-07 US disclosed
US-4247554-A ADMINISTERING A QUINAZOLINONE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-27 US disclosed
US-4096144-A Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-06-20 US disclosed
US-4067868-A Production of quinazolinone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-01-10 US disclosed
US-3953446-A Process for preparing quinazolines SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161402-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE CRYAB, CRYAA, FUCA2 CASR 1994/4885PTGER4 1971/4885PTGIR 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.