Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755387 | 0.78 | KDM4E (0.47) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL6604502 | 0.77 | ADRA1A (0.43) | MAPTGAAKDM4EHTTMAPK1 | |
| SCHEMBL5952401 | 0.76 | MAPT (0.59) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL11051857 | 0.74 | MAPT (0.54) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL27519506 | 0.73 | MEN1 (0.46) | MAPTKDM4EALDH1A1POLBKMT2A | |
| SCHEMBL27545567 | 0.73 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1POLBGABRA1 | |
| SCHEMBL5009932 | 0.73 | MAPT (0.56) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL7755362 | 0.72 | MAPT (0.45) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL10777187 | 0.71 | MAPT (0.59) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL10238812 | 0.71 | GAA (0.58) | MAPTGAAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1261795-A | Compounds and methods | SMITHKLINE BEECHAM CORP (US) | 2000-08-02 | — | — | CN | disclosed |