Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.57 |
| ▸ | NPY1R | P25929 | 10/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.57 |
| ▸ | NPY2R | P49146 | 5/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023009 | 0.83 | METAP2 (0.50) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL27536891 | 0.82 | TLR2 (0.46) | NPY4RNPY1RNPY5RNPY2RTLR2 | |
| SCHEMBL27536888 | 0.82 | TLR2 (0.46) | NPY4RNPY1RNPY5RNPY2RTLR2 | |
| SCHEMBL1593464 | 0.80 | NPY1R (0.70) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL28032820 | 0.80 | NPY1R (0.70) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL28745902 | 0.79 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL370279 | 0.79 | NPY4R (0.78) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL14520583 | 0.79 | NPY4R (0.78) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13188655 | 0.79 | NPY4R (0.78) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29641081 | 0.79 | NPY4R (0.78) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1279666-A | NPY antagonists | ASTRAZENECA AB (SE) | 2001-01-10 | — | — | CN | disclosed |