Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23214483 | 0.71 | CYP3A4 (0.40) | BRD4 | |
| SCHEMBL171024 | 0.69 | BRD4 (0.40) | BRD4 | |
| SCHEMBL13694927 | 0.63 | ALPL (0.34) | ALPLBRD4PLAAALPG | |
| SCHEMBL23214411 | 0.61 | TYR (0.38) | BRD4 | |
| SCHEMBL28439418 | 0.60 | ALDH1A1 (0.37) | — | |
| SCHEMBL12410243 | 0.58 | — | — | |
| SCHEMBL28446255 | 0.58 | KDM4E (0.41) | BRD4 | |
| SCHEMBL11987749 | 0.58 | BRD4 (0.38) | BRD4 | |
| SCHEMBL15573640 | 0.58 | — | — | |
| SCHEMBL23214426 | 0.58 | GRM2 (0.35) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591324-B | Pyrazinone derivatives, preparation and application thereof | 深圳微芯生物科技股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114591324-A | Pyrazinone derivatives, preparation and application thereof | 深圳微芯生物科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |